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Mettl13 protects against cardiac contractile dysfunction by negatively regulating C-Cbl-mediated ubiquitination of SERCA2a in ischemic heart failure.

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作者: Shuting,Yu [1] ; ZhiYong,Sun [1] ; Xiuzhu,Wang [1] ; Tiantian,Ju [1] ; Changhao,Wang [1] ; Yingqi,Liu [1] ; Zhezhe,Qu [1] ; KuiWu,Liu [1] ; Zhongting,Mei [1] ; Na,Li [1] ; Meixi,Lu [2] ; Fan,Wu [1] ; Min,Huang [1] ; Xiaochen,Pang [1] ; Yingqiong,Jia [1] ; Ying,Li [1] ; Yaozhi,Zhang [1] ; Shunkang,Dou [1] ; Jianhao,Jiang [1] ; Xin,Li [1] ; Baofeng,Yang [3] ; Weijie,Du [4]
作者单位: Department of Pharmacology (The State-Province Key Laboratories of Biomedicine Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China. [1] Traditional Chinese Medicine School, Beijing University of Chinese Medicine, Beijing, 100029, China. [2] Department of Pharmacology (The State-Province Key Laboratories of Biomedicine Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China. yangbf@ems.hrbmu.edu.cn. [3] Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China. yangbf@ems.hrbmu.edu.cn. [4] Research Unit of Noninfectious Chronic Diseases in Frigid Zone, Chinese Academy of Medical Sciences, 2019RU070, Harbin, 150081, China. yangbf@ems.hrbmu.edu.cn. [5] Department of Pharmacology (The State-Province Key Laboratories of Biomedicine Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China. duweijie@hrbmu.edu.cn. [6] Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China. duweijie@hrbmu.edu.cn. [7] Research Unit of Noninfectious Chronic Diseases in Frigid Zone, Chinese Academy of Medical Sciences, 2019RU070, Harbin, 150081, China. duweijie@hrbmu.edu.cn. [8]
DOI 10.1007/s11427-022-2351-1
PMID 37450238
发布时间 2023-12-16
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Science China. Life sciences

Science China. Life sciences

2023年66卷12期

2786-2804页

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