Smarca2 genetic ablation is phenotypically benign in a safety assessment of tamoxifen-inducible conditional knockout rats.

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作者： Jonathan,Maher ^[1] ; Nicola,Stagg ^[2] ; Gary,Cain ^[3] ; Roxanne,Andaya ^[3] ; Paula,Katavolos ^[4] ; Fermin,Gallardo-Chang ^[3] ; Anna,Pham ^[3] ; Xiaofen,Ye ^[3] ; Tom,Januario ^[3] ; Tuija,Alcantar ^[3] ; Roger,Caothien ^[3] ; Merone,Roose-Girma ^[3] ; Donglu,Zhang ^[3] ; Ruina,Li ^[3] ; Shu,Chen ^[3] ; Robert L,Yauch ^[5]

作者单位： Genentech, Inc., South San Francisco, CA 94080, USA; Pliant Therapeutics, Inc., South San Francisco, CA 94080, USA. ^[1] Genentech, Inc., South San Francisco, CA 94080, USA; Turning Point Therapeutics, Inc., San Diego, CA 92121, USA. ^[2] Genentech, Inc., South San Francisco, CA 94080, USA. ^[3] Genentech, Inc., South San Francisco, CA 94080, USA; Bristol Myers Squibb, New Brunswick, NJ 08901, USA; 23&Me, Inc., South San Francisco, CA 94080, USA. ^[4] Genentech, Inc., South San Francisco, CA 94080, USA. Electronic address: yauch.bob@gene.com. ^[5]

主题词小鼠(Mice);大鼠(Rats);动物(Animals);他莫昔芬(Tamoxifen);肿瘤(Neoplasms);腺苷三磷酸酶类(Adenosine Triphosphatases);突变(Mutation)

DOI 10.1016/j.taap.2023.116627

PMID 37453479

发布时间 2023-09-08

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Toxicology and applied pharmacology

2023年475卷

116627页

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Smarca2 genetic ablation is phenotypically benign in a safety assessment of tamoxifen-inducible conditional knockout rats.

Toxicology and applied pharmacology

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Toxicology and applied pharmacology

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Smarca2 genetic ablation is phenotypically benign in a safety assessment of tamoxifen-inducible conditional knockout rats.

Toxicology and applied pharmacology

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Toxicology and applied pharmacology

相关期刊

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