Disease progression modelling of Alzheimer's disease using probabilistic principal components analysis.

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作者： Martin,Saint-Jalmes ^[1] ; Victor,Fedyashov ^[2] ; Daniel,Beck ^[3] ; Timothy,Baldwin ^[4] ; Noel G,Faux ^[5] ; Pierrick,Bourgeat ^[6] ; Jurgen,Fripp ^[6] ; Colin L,Masters ^[7] ; Benjamin,Goudey ^[2] ; Alzheimer’s Disease Neuroimaging Initiative

作者单位： ARC Training Centre in Cognitive Computing for Medical Technologies, University of Melbourne, Carlton, VIC, Australia; The Florey Department of Neuroscience and Mental Health, The University of Melbourne, Australia; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Australia. Electronic address: m.saintjalmes@unimelb.edu.au. ^[1] ARC Training Centre in Cognitive Computing for Medical Technologies, University of Melbourne, Carlton, VIC, Australia; The Florey Department of Neuroscience and Mental Health, The University of Melbourne, Australia. ^[2] ARC Training Centre in Cognitive Computing for Medical Technologies, University of Melbourne, Carlton, VIC, Australia; School of Computing and Information Systems, The University of Melbourne, Australia. ^[3] ARC Training Centre in Cognitive Computing for Medical Technologies, University of Melbourne, Carlton, VIC, Australia; School of Computing and Information Systems, The University of Melbourne, Australia; Mohamed bin Zayed University of Artificial Intelligence, Abu Dhabi, United Arab Emirates. ^[4] ARC Training Centre in Cognitive Computing for Medical Technologies, University of Melbourne, Carlton, VIC, Australia; The Florey Department of Neuroscience and Mental Health, The University of Melbourne, Australia; Melbourne Data Analytics Platform, The University of Melbourne, Australia. ^[5] CSIRO Health and Biosecurity, Brisbane, Australia. ^[6] The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Australia. ^[7]

关键词 Alzheimer’s disease Disease progression modeling Latent disease time Machine learning Principal components analysis

主题词人类(Humans);阿尔茨海默病(Alzheimer Disease);横断面研究(Cross-Sectional Studies);疾病恶化(Disease Progression);磁共振成像(Magnetic Resonance Imaging)

DOI 10.1016/j.neuroimage.2023.120279

PMID 37454702

发布时间 2023-08-16

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