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Nasal and blood transcriptomic pathways underpinning the clinical response to grass pollen immunotherapy.

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第一作者： Matthew C,Altman

第一单位： Systems Immunology Division, Benaroya Research Institute, Seattle; Division of Allergy and Infectious Disease, Department of Medicine, University of Washington, Seattle. Electronic address: maltman@benaroyaresearch.org.

作者： Matthew C,Altman ^[1] ; R Max,Segnitz ^[2] ; David,Larson ^[3] ; Naresh Doni,Jayavelu ^[4] ; Malisa T,Smith ^[2] ; Sana,Patel ^[2] ; Guy W,Scadding ^[5] ; Tielin,Qin ^[3] ; Srinath,Sanda ^[6] ; Esther,Steveling ^[5] ; Aarif O,Eifan ^[5] ; Martin,Penagos ^[5] ; Mikila R,Jacobson ^[5] ; Rebecca V,Parkin ^[5] ; Mohamed H,Shamji ^[5] ; Alkis,Togias ^[7] ; Stephen R,Durham ^[5]

作者单位： Systems Immunology Division, Benaroya Research Institute, Seattle; Division of Allergy and Infectious Disease, Department of Medicine, University of Washington, Seattle. Electronic address: maltman@benaroyaresearch.org. ^[1] Division of Allergy and Infectious Disease, Department of Medicine, University of Washington, Seattle. ^[2] Immune Tolerance Network, Bethesda. ^[3] Systems Immunology Division, Benaroya Research Institute, Seattle. ^[4] Immunomodulation and Tolerance Group, Allergy and Clinical Immunology, Department of National Heart and Lung Institute, London. ^[5] Madison Clinic for Pediatric Diabetes, University of California San Francisco, San Francisco. ^[6] The National Institute of Allergy and Infectious Disease, Bethesda. ^[7]

关键词 Allergen immunotherapy RNA sequencing allergic rhinitis subcutaneous immunotherapy sublingual immunotherapy

医学主题词人类(Humans);白细胞, 单核(Leukocytes, Mononuclear);花粉(Pollen);变应原(Allergens);脱敏法, 免疫(Desensitization, Immunologic);梯牧草属(Phleum);注射, 皮下(Injections, Subcutaneous)

DOI 10.1016/j.jaci.2023.06.025

PMID 37460024

发布时间 2025-05-30

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