Powerful and Real-Time Quantification of Antifungal Efficacy against Triazole-Resistant and -Susceptible Aspergillus fumigatus Infections in Galleria mellonella by Longitudinal Bioluminescence Imaging.

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作者： Eliane,Vanhoffelen ^[1] ; Lauren,Michiels ^[1] ; Matthias,Brock ^[2] ; Katrien,Lagrou ^[3] ; Agustin,Reséndiz-Sharpe ^[4] ; Greetje,Vande Velde ^[1]

作者单位： Department of Imaging and Pathology, Biomedical MRI Unit/MoSAIC, KU Leuven, Leuven, Belgium. ^[1] School of Life Sciences, Fungal Biology Group, University of Nottingham, Nottingham, United Kingdom. ^[2] Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical Bacteriology and Mycology, KU Leuven, Leuven, Belgium. ^[3] Department of Laboratory Medicine, National Reference Center for Mycosis, University Hospitals Leuven, Leuven, Belgium. ^[4]

关键词 Aspergillus fumigatus BLI Galleria mellonella antifungal screening antifungal therapy aspergillosis bioluminescence imaging fungal infection triazole resistance

主题词人类(Humans);动物(Animals);小鼠(Mice);抗真菌药(Antifungal Agents);烟曲霉菌(Aspergillus fumigatus);三唑类(Triazoles);结果可重复性(Reproducibility of Results);抗药性, 真菌(Drug Resistance, Fungal);蛾(Moths);幼虫(Larva);微生物敏感性试验(Microbial Sensitivity Tests)

DOI 10.1128/spectrum.00825-23

PMID 37466453

发布时间 2023-10-20

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Microbiology spectrum

2023年11卷4期

e0082523页

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Powerful and Real-Time Quantification of Antifungal Efficacy against Triazole-Resistant and -Susceptible Aspergillus fumigatus Infections in Galleria mellonella by Longitudinal Bioluminescence Imaging.

Microbiology spectrum

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Powerful and Real-Time Quantification of Antifungal Efficacy against Triazole-Resistant and -Susceptible Aspergillus fumigatus Infections in Galleria mellonella by Longitudinal Bioluminescence Imaging.

Microbiology spectrum

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Microbiology spectrum

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