XPO1 is a new target of homoharringtonine (HHT): Making NPMc<sup>+</sup> AML cells much more sensitive to HHT treatment.

导出 LinkOut

翻译打印收藏纠错

第一作者： Jingjing,Xue

第一单位： Liaoning Key Laboratory of Hematopoietic Stem Cell Transplantation and Translational Medicine, Second Hospital of Dalian Medical University, Dalian, China; Department of Hematology, Liaoning Medical Center for Hematopoietic Stem Cell Transplantation, Second Hospital of Dalian Medical University, Dalian, China.

作者： Jingjing,Xue ^[1] ; Peng,Chu ^[2] ; Wenjuan,Gao ^[3] ; Furong,Wang ^[4] ; Yuan,Gao ^[5] ; Shuqing,Liu ^[3] ; Zhijie,Kang ^[6] ; Jinsong,Yan ^[7] ; Haina,Wang ^[8]

作者单位： Liaoning Key Laboratory of Hematopoietic Stem Cell Transplantation and Translational Medicine, Second Hospital of Dalian Medical University, Dalian, China; Department of Hematology, Liaoning Medical Center for Hematopoietic Stem Cell Transplantation, Second Hospital of Dalian Medical University, Dalian, China. ^[1] College of Pharmacy, Dalian Medical University, Dalian, China. ^[2] Department of Biotechnology, Dalian Medical University, Dalian, China. ^[3] Liaoning Key Laboratory of Hematopoietic Stem Cell Transplantation and Translational Medicine, Second Hospital of Dalian Medical University, Dalian, China. ^[4] Department of Hematology, Liaoning Medical Center for Hematopoietic Stem Cell Transplantation, Second Hospital of Dalian Medical University, Dalian, China. ^[5] Department of Hematology, Liaoning Medical Center for Hematopoietic Stem Cell Transplantation, Second Hospital of Dalian Medical University, Dalian, China. Electronic address: kangzhijie2013@163.com. ^[6] Liaoning Key Laboratory of Hematopoietic Stem Cell Transplantation and Translational Medicine, Second Hospital of Dalian Medical University, Dalian, China; Department of Hematology, Liaoning Medical Center for Hematopoietic Stem Cell Transplantation, Second Hospital of Dalian Medical University, Dalian, China. Electronic address: yanjsdmu@dmu.edu.cn. ^[7] Liaoning Key Laboratory of Hematopoietic Stem Cell Transplantation and Translational Medicine, Second Hospital of Dalian Medical University, Dalian, China; Department of Hematology, Liaoning Medical Center for Hematopoietic Stem Cell Transplantation, Second Hospital of Dalian Medical University, Dalian, China. Electronic address: hannah_w@foxmail.com. ^[8]

关键词 AML Homoharringtonine NPM1 Nuclear export signal XPO1

主题词人类(Humans);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);核蛋白质类(Nuclear Proteins);细胞核(Cell Nucleus);细胞质(Cytoplasm);突变(Mutation)

DOI 10.1016/j.bbrc.2023.07.027

PMID 37473530

发布时间 2023-08-22

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交