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Treatment of adult ALL patients with third-generation CD19-directed CAR T cells: results of a pivotal trial.

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第一作者: Maria-Luisa,Schubert
第一单位: Department of Internal Medicine V, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
作者单位: Department of Internal Medicine V, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany. [1] Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.;Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.;Faculty of Biosciences, Heidelberg University, Heidelberg, Germany. [2] Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, Berlin, Germany.;Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.;Department of Hematology, Oncology and Tumor Immunology, Charité University Medicine, Berlin, Germany. [3] Department of Pediatric Hematology, Oncology and Immunology, University Hospital Heidelberg, Heidelberg, Germany. [4] Institute for Clinical Transfusion Medicine and Cell Therapy (IKTZ), German Red Cross Blood Service Baden-Württemberg-Hessen, Heidelberg, Germany. [5] Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, of the Heidelberg University, German Red Cross Blood Service Baden-Württemberg - Hessen, Mannheim, Germany. [6] GRN MVZ Sinsheim, Sinsheim, Germany. [7] Department of Internal Medicine II, University Hospital Frankfurt, Frankfurt, Germany. [8] Department of Hematology and Oncology, University Hospital Oldenburg, Oldenburg, Germany. [9] Department of Hematology and Oncology, Hospital Bielefeld, Bielefeld, Germany. [10] Department of Internal Medicine I, University Hospital Freiburg, Freiburg, Germany. [11] Department of Hematology, Oncology and Immunology, University Hospital Giessen und Marburg, Marburg, Germany. [12] Städtisches Klinikum Karlsruhe, Karlsruhe, Germany. [13] Department of Hematology and Oncology, Center of Internal Medicine, Otto-von-Guericke University Medical Center, Magdeburg, Germany. [14] Department of Internal Medicine II, University Hospital Kiel, Kiel, Germany. [15] Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.;Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.;Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, Berlin, Germany.;Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.;Department of Hematology, Oncology and Tumor Immunology, Charité University Medicine, Berlin, Germany.;German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ)/National Center for Tumor Diseases (NCT), Heidelberg, Germany. [16] Department of Internal Medicine V, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.;German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ)/National Center for Tumor Diseases (NCT), Heidelberg, Germany. [17] Department of Internal Medicine V, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany. michael.schmitt@med.uni-heidelberg.de.;German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ)/National Center for Tumor Diseases (NCT), Heidelberg, Germany. michael.schmitt@med.uni-heidelberg.de. [18]
DOI 10.1186/s13045-023-01470-0
PMID 37481608
发布时间 2023-07-25
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Journal of hematology & oncology

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