CRISPR/Cas9-mediated inactivation of miR-34a and miR-34b/c in HCT116 colorectal cancer cells: comprehensive characterization after exposure to 5-FU reveals EMT and autophagy as key processes regulated by miR-34.
作者:
主题词
人类(Humans);微RNAs(MicroRNAs);HCT116细胞(HCT116 Cells);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);细胞系, 肿瘤(Cell Line, Tumor);结直肠肿瘤(Colorectal Neoplasms);氟尿嘧啶(Fluorouracil);自噬(Autophagy);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic)
DOI
10.1038/s41418-023-01193-2
PMID
37488217
发布时间
2023-08-10
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Cell death and differentiation
2017-2034页
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