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A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation.

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作者单位: Experimental and Molecular Immunology, Dept. of Infection and Immunity (DII), Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg.;Immunology & Genetics, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7, Avenue des Hauts Fourneaux, Esch-sur-Alzette, Luxembourg. [1] Institute of Experimental Immunology, Inflammation Research, University of Zurich, 8057 Zurich, Switzerland.;Center for Fundamental Immunology, Benaroya Research Institute; Seattle, WA 98101, USA. [2] Molecular Disease Mechanisms Group, Department of Life Sciences and Medicine, University of Luxembourg, Belval, Luxembourg. [3] National Center of Pathology (NCP), Laboratoire National de Santé (LNS), Dudelange, Luxembourg.;Luxembourg Center of Neuropathology (LCNP), Dudelange, L-3555, Luxembourg. [4] Department of Environmental Health Sciences, Yale School of Public Health, New Haven, Connecticut, USA. [5] Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY 14642, USA. [6] Department of Molecular Medicine II, Medical Faculty Heinrich Heine University Düsseldorf, Germany. [7] Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany. [8] Institute of Experimental Immunology, Inflammation Research, University of Zurich, 8057 Zurich, Switzerland. [9] National Center of Pathology (NCP), Laboratoire National de Santé (LNS), Dudelange, Luxembourg.;Luxembourg Center of Neuropathology (LCNP), Dudelange, L-3555, Luxembourg.;Department of Life Sciences and Medicine (DLSM), University of Luxembourg, Esch-sur-Alzette, Luxembourg.;Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette, L-4362, Luxembourg.;Faculty of Science, Technology and Medicine (FSTM), University of Luxembourg, Esch-sur-Alzette, Luxembourg.;Department of Cancer Research (DoCR), Luxembourg Institute of Health (LIH), Luxembourg, L-1526, Luxembourg. [10] Experimental and Molecular Immunology, Dept. of Infection and Immunity (DII), Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg.;Immunology & Genetics, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7, Avenue des Hauts Fourneaux, Esch-sur-Alzette, Luxembourg.;Odense Research Center for Anaphylaxis (ORCA), Department of Dermatology and Allergy Center, Odense University Hospital, University of Southern Denmark, Odense, Denmark. [11]
DOI 10.1101/2023.07.06.547932
PMID 37489135
发布时间 2024-08-07
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