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Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques.

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作者单位: Division of Microbiology and Immunology, Emory National Primate Research Center, Emory University, Atlanta, GA 30329, USA. [1] Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany. [2] Emory NPRC Genomics Core Emory National Primate Research Center, Emory University, Atlanta, GA 30329, USA. [3] Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. [4] Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 76100, Israel. [5] Center for Innate Immunity and Immune Disease, Department of Immunology, University of Washington School of Medicine, Seattle, WA 98109, USA. [6] Division of Pathology, Emory National Primate Research Center, Emory University, Atlanta, GA 30329, USA. [7] StageBio, 5930 Main St., Mount Jackson, VA 22842, USA. [8] Division of Animal Resources, Emory National Primate Research Center, Emory University, Atlanta, GA 30329, USA. [9] RNA Vaccines Group, Access to Advanced Health Institute, Seattle, WA 98102, USA. [10] Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, GA 30322, USA. [11] Division of Microbiology and Immunology, Emory National Primate Research Center, Emory University, Atlanta, GA 30329, USA.;Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, GA 30322, USA. [12] Department of Medicine, School of Medicine, Emory University, Atlanta, GA 30322, USA. [13] Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97006, USA. [14] Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97006, USA.;Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.;Department of Clinical Medicine, Aarhus University, Aarhus 8000, Denmark.;School of Health and Biomedical Sciences, College of Science, Engineering and Health, RMIT University, Melbourne, VIC 3000, Australia. [15] Division of Immunology, Tulane National Primate Research Center, Covington, LA 70433, USA.;Department of Microbiology and Immunology, Tulane School of Medicine, New Orleans, LA 70112, USA. [16] Division of Microbiology and Immunology, Emory National Primate Research Center, Emory University, Atlanta, GA 30329, USA.;Infectious Disease Division, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA. [17] Division of Microbiology and Immunology, Emory National Primate Research Center, Emory University, Atlanta, GA 30329, USA.;Emory NPRC Genomics Core Emory National Primate Research Center, Emory University, Atlanta, GA 30329, USA.;Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, GA 30322, USA. [18]
DOI 10.1126/sciimmunol.adg0033
PMID 37506197
发布时间 2024-11-01
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Science immunology

Science immunology

2023年8卷85期

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