Clinical outcomes and safety of anakinra in the treatment of multisystem inflammatory syndrome in children: a single center observational study.

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作者： Brian L P,Dizon ^[1] ; Christopher,Redmond ^[2] ; Emily C,Gotschlich ^[1] ; Sangeeta,Sule ^[2] ; Tova,Ronis ^[1] ; Kathleen M,Vazzana ^[1] ; Matthew A,Sherman ^[3] ; Rachael,Connor ^[1] ; Abigail,Bosk ^[3] ; Niti,Dham ^[1] ; Ashraf S,Harahsheh ^[4] ; Elizabeth,Wells ^[1] ; Roberta,DeBiasi ^[1] ; Hemalatha,Srinivasalu ^[1]

作者单位： Division of Rheumatology, Children's National Hospital, Washington, DC, USA. ^[1] Rheumatology Fellowship and Training Branch, The National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, USA. ^[2] Department of Pediatrics, George Washington University School of Medicine & Health Sciences, Washington, DC, USA. ^[3] Department of Pediatric Rheumatology, Arnold Palmer Hospital for Children, Orlando, FL, USA. ^[4] Division of Cardiology, Children's National Hospital, Washington, DC, USA. ^[5] Division of Neurology, Children's National Hospital, Washington, DC, USA. ^[6] Division of Infectious Diseases, Children's National Hospital, Washington, DC, USA. ^[7] Division of Rheumatology, Children's National Hospital, Washington, DC, USA. HSriniva@childrensnational.org. ^[8] Department of Pediatrics, George Washington University School of Medicine & Health Sciences, Washington, DC, USA. HSriniva@childrensnational.org. ^[9]

关键词 Anakinra Cardiac dysfunction Multisystem inflammatory syndrome in children SARS-CoV2 Therapy

主题词人类(Humans);白细胞介素1受体拮抗蛋白质(Interleukin 1 Receptor Antagonist Protein);免疫球蛋白类, 静脉内(Immunoglobulins, Intravenous);全身炎症反应综合征(Systemic Inflammatory Response Syndrome);发热(Fever)

DOI 10.1186/s12969-023-00858-z

PMID 37525200

发布时间 2023-08-03

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