Tarsal exposure to atovaquone inhibits chikungunya virus transmission by Aedes aegypti mosquitoes, but not the transmission of Zika virus.

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作者： Lanjiao,Wang ^[1] ; Aboubakar,Sanon ^[2] ; Zakiyatul,Khoiriyah ^[3] ; Sam,Verwimp ^[1] ; Rana,Abdelnabi ^[1] ; Leen,Delang ^[4]

作者单位： KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, B-3000, Leuven, Belgium. ^[1] KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, B-3000, Leuven, Belgium; Laboratoire d'Entomologie Fondamentale et Appliquée, Université Joseph Ki-Zerbo, Burkina Faso. ^[2] KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, B-3000, Leuven, Belgium; Laboratory of Virology, Wageningen University and Research, 6708 PB, Wageningen, the Netherlands. ^[3] KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, B-3000, Leuven, Belgium. Electronic address: leen.delang@kuleuven.be. ^[4]

关键词 Aedes aegypti Atovaquone Chikungunya virus Tarsal exposure Virus transmission Zika virus

主题词动物(Animals);女(雌)性(Female);切昆贡亚病毒(Chikungunya virus);伊蚊属(Aedes);阿托伐醌(Atovaquone);抗病毒药(Antiviral Agents)

DOI 10.1016/j.antiviral.2023.105694

PMID 37532005

发布时间 2023-08-29

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