Presymptomatic and early pathological features of MAPT-associated frontotemporal lobar degeneration.

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第一作者： Lucia Aa,Giannini

第一单位： Department of Neurology and Alzheimer Center Erasmus MC, Erasmus University Medical Center, Rotterdam, 3015 GD, The Netherlands.

作者： Lucia Aa,Giannini ^[1] ; Merel O,Mol ^[1] ; Ana,Rajicic ^[1] ; Renee,van Buuren ^[1] ; Lana,Sarkar ^[1] ; Sanaz,Arezoumandan ^[2] ; Daniel T,Ohm ^[3] ; David J,Irwin ^[2] ; Annemieke Jm,Rozemuller ^[3] ; Netherlands Brain Bank ^[2] ; John C,van Swieten ^[3] ; Harro,Seelaar ^[4]

作者单位： Department of Neurology and Alzheimer Center Erasmus MC, Erasmus University Medical Center, Rotterdam, 3015 GD, The Netherlands. ^[1] Digital Neuropathology Laboratory, Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. ^[2] Penn Frontotemporal Degeneration Center, Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. ^[3] Department of Pathology, Amsterdam Neuroscience, Amsterdam University Medical Center, location VUmc, Amsterdam, 1081 HZ, The Netherlands. ^[4] Department of Neurology and Alzheimer Center Erasmus MC, Erasmus University Medical Center, Rotterdam, 3015 GD, The Netherlands. h.seelaar@erasmusmc.nl. ^[5]

关键词 Early pathology Frontotemporal lobar degeneration MAPT gene Neuronal degeneration Tau burden

主题词人类(Humans);老年人(Aged);中年人(Middle Aged);额颞叶变性(Frontotemporal Lobar Degeneration);额颞叶痴呆(Frontotemporal Dementia);tau蛋白质类(tau Proteins);阿尔茨海默病(Alzheimer Disease);扣带回(Gyrus Cinguli)

DOI 10.1186/s40478-023-01588-9

PMID 37533060

发布时间 2024-03-15

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Acta neuropathologica communications

2023年11卷1期

126页

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Presymptomatic and early pathological features of MAPT-associated frontotemporal lobar degeneration.

Acta neuropathologica communications

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Acta neuropathologica communications

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Presymptomatic and early pathological features of MAPT-associated frontotemporal lobar degeneration.

Acta neuropathologica communications

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Acta neuropathologica communications

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