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A novel auxin-inducible degron system for rapid, cell cycle-specific targeted proteolysis.

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第一作者： Marina,Capece

第一单位： Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University, 43210, Columbus, OH, USA.;The Ohio State University Wexner Medical Center and Comprehensive Cancer Center, 43210, Columbus, OH, USA.

作者： Marina,Capece ^[1] ; Anna,Tessari ^[1] ; Joseph,Mills ^[1] ; Gian Luca Rampioni,Vinciguerra ^[1] ; Darian,Louke ^[2] ; Chenyu,Lin ^[1] ; Bryan K,McElwain ^[1] ; Wayne O,Miles ^[1] ; Vincenzo,Coppola ^[1] ; Alexander E,Davies ^[2] ; Dario,Palmieri ^[3] ; Carlo M,Croce ^[4]

作者单位： Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University, 43210, Columbus, OH, USA.;The Ohio State University Wexner Medical Center and Comprehensive Cancer Center, 43210, Columbus, OH, USA. ^[1] The Ohio State University Wexner Medical Center and Comprehensive Cancer Center, 43210, Columbus, OH, USA.;Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, 43210, Columbus, OH, USA. ^[2] Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University, 43210, Columbus, OH, USA. dario.palmieri@osumc.edu.;The Ohio State University Wexner Medical Center and Comprehensive Cancer Center, 43210, Columbus, OH, USA. dario.palmieri@osumc.edu.;Gene Editing Shared Resource, The Ohio State University Wexner Medical Center and Comprehensive Cancer Center, 43210, Columbus, OH, USA. dario.palmieri@osumc.edu. ^[3] Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University, 43210, Columbus, OH, USA. carlo.croce@osumc.edu.;The Ohio State University Wexner Medical Center and Comprehensive Cancer Center, 43210, Columbus, OH, USA. carlo.croce@osumc.edu. ^[4]

医学主题词吲哚乙酸类(Indoleacetic Acids);蛋白质类(Proteins);细胞周期(Cell Cycle);细胞分裂(Cell Division)

DOI 10.1038/s41418-023-01191-4

PMID 37537305

发布时间 2024-09-30

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准确一般字义偏差语意偏离译文作用小提交