A top-down proteomic approach reveals a salivary protein profile able to classify Parkinson's disease with respect to Alzheimer's disease patients and to healthy controls.

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作者： Cristina,Contini ^[1] ; Laura,Fadda ^[2] ; Greca,Lai ^[1] ; Carla,Masala ^[3] ; Alessandra,Olianas ^[1] ; Massimo,Castagnola ^[4] ; Irene,Messana ^[5] ; Federica,Iavarone ^[6] ; Alessandra,Bizzarro ^[7] ; Carlo,Masullo ^[7] ; Paolo,Solla ^[8] ; Giovanni,Defazio ^[9] ; Barbara,Manconi ^[10] ; Giacomo,Diaz ^[2] ; Tiziana,Cabras ^[1]

作者单位： Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria Monserrato, Monserrato, CA, Italy. ^[1] Department of Medical Sciences and Public Health, Institute of Neurology, Cagliari, Italy. ^[2] Department of Biomedical Sciences University of Cagliari, Cittadella Univ. Monserrato, Monserrato, Italy. ^[3] Proteomics Laboratory. European Center for Brain Research, (IRCCS) Santa Lucia Foundation, Rome, Italy. ^[4] Consiglio Nazionale delle Ricerche, Istituto di Scienze e Tecnologie Chimiche "Giulio Natta", Rome, Italy. ^[5] Department of Basic Biotechnological Sciences, Intensive and Perioperative Clinics, Rome, Italy. ^[6] Fondazione Policlinico Universitario "A. Gemelli", IRCCS, Rome, Italy. ^[7] Department of Geriatrics, Orthopaedics and Rheumatology, Rome, Italy. ^[8] Department of Neuroscience, Neurology Section, Università Cattolica del Sacro Cuore Rome, Rome, Italy. ^[9] Neurological Unit, Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy. ^[10]

关键词 Alzheimer's disease Parkinson's disease S100A9 cystatins salivary proteomics