SUMOylation of the cardiac sodium channel Na<sub>V</sub>1.5 modifies inward current and cardiac excitability.

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第一作者： Jin-Young,Yoon

第一单位： Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa, Iowa City, Iowa; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, Iowa.

作者： Jin-Young,Yoon ^[1] ; Alexander M,Greiner ^[2] ; Julia S,Jacobs ^[2] ; Young-Rae,Kim ^[2] ; Tyler P,Rasmussen ^[2] ; William J,Kutschke ^[2] ; Daniel S,Matasic ^[2] ; Ajit,Vikram ^[1] ; Ravinder R,Gaddam ^[1] ; Haider,Mehdi ^[1] ; Kaikobad,Irani ^[3] ; Barry,London ^[4]

作者单位： Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa, Iowa City, Iowa; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, Iowa. ^[1] Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa, Iowa City, Iowa. ^[2] Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa, Iowa City, Iowa; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, Iowa; Fraternal Order of Eagles Diabetes Research Center, Pappajohn Biomedical Institute, and Heart and Vascular Center, University of Iowa, Iowa City, Iowa. Electronic address: kaikobad-irani@uiowa.edu. ^[3] Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa, Iowa City, Iowa; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, Iowa. Electronic address: barry-london@uiowa.edu. ^[4]

关键词 Arrhythmia Na(V)1.5 SENP SUMOylation Sodium current