Mesenchymal stem cells shift the pro-inflammatory phenotype of neutrophils to ameliorate acute lung injury.

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作者： Bing,Feng ^[1] ; Xudong,Feng ^[2] ; Yingduo,Yu ^[1] ; Haoying,Xu ^[2] ; Qingqing,Ye ^[1] ; Ruitian,Hu ^[2] ; Xinru,Fang ^[1] ; Feiqiong,Gao ^[2] ; Jian,Wu ^[1] ; Qiaoling,Pan ^[2] ; Jiong,Yu ^[3] ; Guanjing,Lang ^[4] ; Lanjuan,Li ^[1] ; Hongcui,Cao ^[2]

作者单位： State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Rd., Hangzhou, 310003, China. ^[1] National Clinical Research Center for Infectious Diseases, 79 Qingchun Rd., Hangzhou, 310003, China. ^[2] Key Laboratory of Diagnosis and Treatment of Aging and Physic-Chemical Injury Diseases of Zhejiang Province, 79 Qingchun Rd, Hangzhou, 310003, China. ^[3] Department of Chemistry, Duke University, 124 Science Drive, Durham, NC, 27708, USA. ^[4] Jinan Microecological Biomedicine Shandong Laboratory, Jinan, 250117, Shandong, China. ^[5] State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Rd., Hangzhou, 310003, China. hccao@zju.edu.cn. ^[6] National Clinical Research Center for Infectious Diseases, 79 Qingchun Rd., Hangzhou, 310003, China. hccao@zju.edu.cn. ^[7] Key Laboratory of Diagnosis and Treatment of Aging and Physic-Chemical Injury Diseases of Zhejiang Province, 79 Qingchun Rd, Hangzhou, 310003, China. hccao@zju.edu.cn. ^[8]

关键词 Acute lung injury Mesenchymal stem cell Mouse model Neutrophil Single-cell RNA sequencing