Transmitted/founder SHIV.D replicates in the brain, causes neuropathogenesis, and persists on combination antiretroviral therapy in rhesus macaques.

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第一作者： Rachel M,Podgorski

第一单位： Center for NeuroVirology and Gene Editing, Department of Microbiology, Immunology, and Inflammation, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.

作者： Rachel M,Podgorski ^[1] ; Jake A,Robinson ^[1] ; Mandy D,Smith ^[1] ; Suvadip,Mallick ^[2] ; Huaqing,Zhao ^[3] ; Ronald S,Veazey ^[4] ; Dennis L,Kolson ^[5] ; Katharine J,Bar ^[6] ; Tricia H,Burdo ^[7]

作者单位： Center for NeuroVirology and Gene Editing, Department of Microbiology, Immunology, and Inflammation, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA. ^[1] Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. ^[2] Center for Biostatistics and Epidemiology, Department of Biomedical Education and Data Science, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA. ^[3] Tulane National Primate Research Center, Tulane School of Medicine, Covington, LA, USA. ^[4] Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. ^[5] Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. bark@pennmedicine.upenn.edu. ^[6] Center for NeuroVirology and Gene Editing, Department of Microbiology, Immunology, and Inflammation, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA. burdot@temple.edu. ^[7]

关键词 HIV NeuroHIV Non-human primates Persistence SHIV