SHFL inhibits enterovirus A71 infection by triggering degradation of viral 3D<sup>pol</sup> protein via the ubiquitin-proteasome pathway.

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作者： Chahui,Tan ^[1] ; Xingliang,Qin ^[2] ; Yongyao,Tan ^[3] ; Xinhuai,Dong ^[1] ; Delin,Chen ^[2] ; Linyue,Liang ^[1] ; Jinling,Li ^[2] ; Ruoxi,Niu ^[4] ; Kaiyuan,Cao ^[1] ; Zhenjian,He ^[2] ; Guohong,Wei ^[1] ; Mingxing,Huang ^[2] ; Xun,Zhu ^[1]

作者单位： Key Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou, China. ^[1] Department of Immunology and Microbiology, Zhongshan School of Medicine, Research Center for Clinical Laboratory Standard, Sun Yat-sen University, Guangzhou, China. ^[2] Department of Laboratory Medicine, Changsha Medical University, Changsha, China. ^[3] Shunde Hospital, Medical Research Center, Southern Medical University (The First People's Hospital of Shunde), Foshan, China. ^[4] Department of Clinical Laboratory Medicine, University-Town Hospital of Chongqing Medical University, Chongqing, China. ^[5] School of Public Health, Sun Yat-sen University, Guangzhou, China. ^[6] Department of Endocrinology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. ^[7] Central Laboratory, The Third People's Hospital of Zhuhai, Zhuhai, China. ^[8] Guangdong Provincial Key Laboratory of Orthopedics and Traumatology, Guangzhou, China. ^[9]

关键词 SHFL enterovirus A71 hand-foot-mouth disease interferon interferon-stimulated genes