Propofol Inhibits Glioma Stem Cell Growth and Migration and Their Interaction with Microglia via BDNF-AS and Extracellular Vesicles.

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第一作者： Rephael,Nizar

第一单位： The Mina and Everard Goodman Faculty of Life Sciences, Institute of Nanotechnology and Advanced Materials (BINA), Bar-Ilan University, Ramat-Gan 52900, Israel.

作者： Rephael,Nizar ^[1] ; Simona,Cazacu ^[2] ; Cunli,Xiang ^[2] ; Matan,Krasner ^[1] ; Efrat,Barbiro-Michaely ^[1] ; Doron,Gerber ^[1] ; Jonathan,Schwartz ^[1] ; Iris,Fried ^[3] ; Shira,Yuval ^[3] ; Aharon,Brodie ^[4] ; Gila,Kazimirsky ^[1] ; Naama,Amos ^[1] ; Ron,Unger ^[1] ; Stephen,Brown ^[5] ; Lisa,Rogers ^[6] ; Donald H,Penning ^[2] ; Chaya,Brodie ^[7]

作者单位： The Mina and Everard Goodman Faculty of Life Sciences, Institute of Nanotechnology and Advanced Materials (BINA), Bar-Ilan University, Ramat-Gan 52900, Israel. ^[1] Davidson Laboratory of Cell Signaling and Tumorigenesis, Hermelin Brain Tumor Center, Department of Neurosurgery, Henry Ford Health, Detroit, MI 48202, USA. ^[2] Pediatric Hematology Oncology Unit, Shaare Zedek Hospital, Jerusalem 9103102, Israel. ^[3] EviCure Ltd., Ness Ziona 7670306, Israel. ^[4] Radiation Oncology, Henry Ford Health, Detroit, MI 48202, USA. ^[5] Department of Neurosurgery, Henry Ford Health, Detroit, MI 48202, USA. ^[6] Anesthesiology, Pain Management & Perioperative Medicine, Henry Ford Health, Detroit, MI 48202, USA. ^[7]

关键词 BDNF-AS extracellular vesicles glioblastoma glioma stem cells microglia propofol

主题词人类(Humans);脑肿瘤(Brain Neoplasms);脑源性神经营养因子(Brain-Derived Neurotrophic Factor);胶质母细胞瘤(Glioblastoma);神经胶质瘤(Glioma);小神经胶质细胞(Microglia);肿瘤干细胞(Neoplastic Stem Cells);二异丙酚(Propofol)

DOI 10.3390/cells12151921

PMID 37566001

发布时间 2023-08-15

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2023年12卷15期

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Propofol Inhibits Glioma Stem Cell Growth and Migration and Their Interaction with Microglia via BDNF-AS and Extracellular Vesicles.

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Propofol Inhibits Glioma Stem Cell Growth and Migration and Their Interaction with Microglia via BDNF-AS and Extracellular Vesicles.

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