Therapeutic Effect of C-Vx Substance in K18-hACE2 Transgenic Mice Infected with SARS-CoV-2.

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作者： Hivda,Ulbegi Polat ^[1] ; Irem,Abaci ^[1] ; Arzu,Tas Ekiz ^[2] ; Ozge,Aksoy ^[1] ; Fatma Betul,Oktelik ^[1] ; Vuslat,Yilmaz ^[3] ; Saban,Tekin ^[4] ; Alper,Okyar ^[5] ; Oral,Oncul ^[6] ; Gunnur,Deniz ^[7]

作者单位： TUBITAK Marmara Research Center, Kocaeli 41470, Türkiye. ^[1] Department of Biotechnology, Institute of Biotechnology, Gebze Technical University, Kocaeli 41400, Türkiye. ^[2] Department of Molecular Biology and Genetics, Institute of Sciences, Yildiz Technical University, Istanbul 34220, Türkiye. ^[3] Department of Immunology, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul 34452, Türkiye. ^[4] Department of Neuroscience, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul 34452, Türkiye. ^[5] Department of Medical Biology, University of Health Sciences, Istanbul 34865, Türkiye. ^[6] Department of Pharmacology, Faculty of Pharmacy, Istanbul University, Istanbul 34452, Türkiye. ^[7] Department of Infectious Diseases and Clinical Microbiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul 34452, Türkiye. ^[8]

关键词 C-Vx COVID-19 SARS-CoV-2 antiviral cytokines neutralization

主题词人类(Humans);小鼠(Mice);动物(Animals);小鼠, 转基因(Mice, Transgenic);抗病毒药(Antiviral Agents);细胞因子类(Cytokines);疾病模型, 动物(Disease Models, Animal)

DOI 10.3390/ijms241511957

PMID 37569331

发布时间 2023-08-14

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