Leucine suppresses glucagon secretion from pancreatic islets by directly modulating α-cell cAMP.

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第一作者： Emily R,Knuth

第一单位： Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, WI 53705, USA.

作者： Emily R,Knuth ^[1] ; Hannah R,Foster ^[1] ; Erli,Jin ^[1] ; Matthew J,Merrins ^[2]

作者单位： Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, WI 53705, USA. ^[1] Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, WI 53705, USA.;William S. Middleton Memorial Veterans Hospital, Madison, WI 53705, USA. ^[2]

关键词 Ca2+Glucagon secretion amino acid metabolism cAMP glutamate dehydrogenase pancreatic islet somatostatin receptor 2 (Sstr2)α-cell

DOI 10.1101/2023.07.31.551113

PMID 37577685

发布时间 2024-09-23

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Leucine suppresses glucagon secretion from pancreatic islets by directly modulating α-cell cAMP.

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Leucine suppresses glucagon secretion from pancreatic islets by directly modulating α-cell cAMP.

bioRxiv

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