Glutamine Production by Glul Promotes Thermogenic Adipocyte Differentiation Through Prdm9-Mediated H3K4me3 and Transcriptional Reprogramming.

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第一作者： Xiaowen,Pan

第一单位： Department of Pathology and Pathophysiology and Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

作者： Xiaowen,Pan ^[1] ; Lingxia,Ye ^[2] ; Xiaozhen,Guo ^[3] ; Weihua,Wang ^[4] ; Ziyin,Zhang ^[1] ; Qintao,Wang ^[2] ; Jingjing,Huang ^[1] ; Jingya,Xu ^[2] ; Yanhan,Cai ^[1] ; Xinxin,Shou ^[2] ; Yuting,Wang ^[3] ; Yu,Feng ^[1] ; Cen,Xie ^[2] ; Pengfei,Shan ^[3] ; Zhuo-Xian,Meng ^[1]

作者单位： Department of Pathology and Pathophysiology and Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. ^[1] Key Laboratory of Disease Proteomics of Zhejiang Province, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. ^[2] Department of Endocrinology and Metabolism, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. ^[3] State Key Laboratory of Drug Research, Shanghai Institute of Material Medical, Chinese Academy of Sciences, Shanghai, China. ^[4] Department of Endocrinology, The Second Affiliated Hospital of Soochow University, Suzhou, China. ^[5] Department of Geriatrics, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. ^[6] Chronic Disease Research Institute, Zhejiang University School of Public Health, Hangzhou, China. ^[7]

DOI 10.2337/db23-0162

PMID 37579296

发布时间 2023-10-20

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Diabetes

2023年72卷11期

1574-1596页

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Glutamine Production by Glul Promotes Thermogenic Adipocyte Differentiation Through Prdm9-Mediated H3K4me3 and Transcriptional Reprogramming.

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Glutamine Production by Glul Promotes Thermogenic Adipocyte Differentiation Through Prdm9-Mediated H3K4me3 and Transcriptional Reprogramming.

Diabetes

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Diabetes

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