Allosteric modulation of SHP2: Quest from known to unknown.

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第一作者： Ning,Wang

第一单位： Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China.

作者： Ning,Wang ^[1] ; Shilin,Zhu ^[2] ; Dan,Lv ^[3] ; Yajun,Wang ^[1] ; Muhammad B,Khawar ^[2] ; Haibo,Sun ^[4]

作者单位： Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China. ^[1] Jiangsu Key Laboratory of Experimental & Translational Non-coding RNA Research, Yangzhou, China. ^[2] Department of Oncology, Haian Hospital of Traditional Chinese Medicine, Haian, China. ^[3] School of Life Sciences, Anqing Normal University, Anqing, China. ^[4] Applied Molecular Biology and Biomedicine Lab, Department of Zoology, University of Narowal, Narowal, Pakistan. ^[5]

关键词 SHP2's inhibitors allosteric drugs allosteric regulation protein tyrosine phosphatase

主题词人类(Humans);蛋白质酪氨酸磷酸酶, 非受体11型(Protein Tyrosine Phosphatase, Non-Receptor Type 11);肿瘤(Neoplasms);氨基酸序列(Amino Acid Sequence);抗肿瘤药(Antineoplastic Agents);细胞周期(Cell Cycle);酶抑制剂(Enzyme Inhibitors)

DOI 10.1002/ddr.22100

PMID 37583266

发布时间 2023-11-14

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