Circulating Biomarkers Instead of Genotyping to Establish Metabolizer Phenotypes.

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作者： Roman,Tremmel ^[1] ; Ute,Hofmann ^[2] ; Mathias,Haag ^[1] ; Elke,Schaeffeler ^[2] ; Matthias,Schwab ^[1]

作者单位： Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany; email: matthias.schwab@ikp-stuttgart.de. ^[1] University of Tuebingen, Tuebingen, Germany. ^[2] Cluster of Excellence iFIT (EXC2180) "Image-Guided and Functionally Instructed Tumor Therapies," University of Tuebingen, Tuebingen, Germany. ^[3] Departments of Clinical Pharmacology, and Pharmacy and Biochemistry, University of Tuebingen, Tuebingen, Germany. ^[4] German Cancer Consortium (DKTK), German Cancer Research Center Heidelberg (DKFZ), Partner Site, Tübingen, Germany. ^[5]

关键词 drug metabolism exosomes genomics liquid biopsy metabolomics phenotype

主题词人类(Humans);人工智能(Artificial Intelligence);基因型(Genotype);表型(Phenotype)

DOI 10.1146/annurev-pharmtox-032023-121106

PMID 37585662

发布时间 2024-01-24

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