Targeting Desulfovibrio vulgaris flagellin-induced NAIP/NLRC4 inflammasome activation in macrophages attenuates ulcerative colitis.

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作者： Yaping,An ^[1] ; Zihan,Zhai ^[1] ; Xin,Wang ^[1] ; Yiyun,Ding ^[1] ; Linlin,He ^[1] ; Lingfeng,Li ^[1] ; Qi,Mo ^[1] ; Chenlu,Mu ^[1] ; Runxiang,Xie ^[1] ; Tianyu,Liu ^[1] ; Weilong,Zhong ^[1] ; Bangmao,Wang ^[1] ; Hailong,Cao ^[2]

作者单位： Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, National Key Clinical Specialty, Tianjin Institute of Digestive Diseases, Tianjin Key Laboratory of Digestive Diseases, Tianjin, China. ^[1] Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, National Key Clinical Specialty, Tianjin Institute of Digestive Diseases, Tianjin Key Laboratory of Digestive Diseases, Tianjin, China. Electronic address: caohailong@tmu.edu.cn. ^[2]

关键词 Desulfovibrio vulgaris Eugeniin NAIP/NLRC4 inflammasome Pyroptosis Ulcerative colitis

主题词人类(Humans);小鼠(Mice);动物(Animals);炎性体(Inflammasomes);鞭毛蛋白(Flagellin);普通脱硫弧菌(Desulfovibrio vulgaris);结肠炎, 溃疡性(Colitis, Ulcerative);巨噬细胞(Macrophages);钙结合蛋白质类(Calcium-Binding Proteins);CARD信号接头蛋白质类(CARD Signaling Adaptor Proteins);神经细胞凋亡抑制蛋白质(Neuronal Apoptosis-Inhibitory Protein)

DOI 10.1016/j.jare.2023.08.008

PMID 37586642

发布时间 2023-10-10

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Journal of advanced research

2023年52卷

219-232页

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Targeting Desulfovibrio vulgaris flagellin-induced NAIP/NLRC4 inflammasome activation in macrophages attenuates ulcerative colitis.

Journal of advanced research

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Journal of advanced research

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Targeting Desulfovibrio vulgaris flagellin-induced NAIP/NLRC4 inflammasome activation in macrophages attenuates ulcerative colitis.

Journal of advanced research

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Journal of advanced research

相关期刊

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