ScRNA-seq defines dynamic T-cell subsets in longitudinal colon and peripheral blood samples in immune checkpoint inhibitor-induced colitis.

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作者： Jacqueline E,Mann ^[1] ; Liliana,Lucca ^[2] ; Matthew R,Austin ^[1] ; Ross D,Merkin ^[1] ; Marie E,Robert ^[3] ; Badr,Al Bawardy ^[4] ; Khadir,Raddassi ^[2] ; Lilach,Aizenbud ^[1] ; Nikhil S,Joshi ^[5] ; David A,Hafler ^[2] ; Clara,Abraham ^[5] ; Kevan C,Herold ^[4] ; Harriet M,Kluger ^[5]

作者单位： Department of Internal Medicine (Medical Oncology), Yale School of Medicine, New Haven, Connecticut, USA. ^[1] Department of Neurology, Yale School of Medicine, New Haven, Connecticut, USA. ^[2] Department of Pathology, Yale School of Medicine, New Haven, Connecticut, USA. ^[3] Department of Internal Medicine (Digestive Diseases), Yale University, New Haven, Connecticut, USA. ^[4] Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut, USA. ^[5] Department of Internal Medicine (Endocrinology), Yale School of Medicine, New Haven, Connecticut, USA. ^[6] Department of Internal Medicine (Medical Oncology), Yale School of Medicine, New Haven, Connecticut, USA Harriet.Kluger@Yale.edu. ^[7]

关键词 CD8-Positive T-Lymphocytes Immune Checkpoint Inhibitors Immunotherapy Programmed Cell Death 1 Receptor T-Lymphocytes

主题词人类(Humans);结肠炎(Colitis);T淋巴细胞亚群(T-Lymphocyte Subsets);皮肤肿瘤(Skin Neoplasms)

DOI 10.1136/jitc-2023-007358

PMID 37586769

发布时间 2024-04-30

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Journal for immunotherapy of cancer

2023年11卷8期

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ScRNA-seq defines dynamic T-cell subsets in longitudinal colon and peripheral blood samples in immune checkpoint inhibitor-induced colitis.

Journal for immunotherapy of cancer

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Journal for immunotherapy of cancer

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ScRNA-seq defines dynamic T-cell subsets in longitudinal colon and peripheral blood samples in immune checkpoint inhibitor-induced colitis.

Journal for immunotherapy of cancer

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Journal for immunotherapy of cancer

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