KCTD1 is a new modulator of the KCASH family of Hedgehog suppressors.

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作者： A,Di Fiore ^[1] ; S,Bellardinelli ^[2] ; L,Pirone ^[3] ; R,Russo ^[4] ; A,Angrisani ^[1] ; G,Terriaca ^[1] ; M,Bowen ^[2] ; F,Bordin ^[1] ; Z M,Besharat ^[2] ; G,Canettieri ^[5] ; F,Fabretti ^[5] ; S,Di Gaetano ^[3] ; L,Di Marcotullio ^[5] ; E,Pedone ^[3] ; M,Moretti ^[6] ; E,De Smaele ^[7]

作者单位： Department of Experimental Medicine, Sapienza University of Rome, Italy; Department of Molecular Medicine, Sapienza University of Rome, Italy. ^[1] Department of Experimental Medicine, Sapienza University of Rome, Italy. ^[2] Institute of Biostructures and Bioimaging, CNR, Naples 80131, Italy. ^[3] Institute of Biostructures and Bioimaging, CNR, Naples 80131, Italy; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli, Caserta, Italy. ^[4] Department of Molecular Medicine, Sapienza University of Rome, Italy. ^[5] Department of Experimental Medicine, Sapienza University of Rome, Italy; Neuromed Institute, Pozzilli 86077, Italy. ^[6] Department of Experimental Medicine, Sapienza University of Rome, Italy. Electronic address: enrico.desmaele@uniroma1.it. ^[7]

关键词 Cancer HDAC1 Hedgehog KCASH1 KCASH2 KCASH3 KCTD1 KCTD11 KCTD21 KCTD6 Medulloblastoma Protein-stability Ubiquitination

主题词男(雄)性(Male);人类(Humans);猬蛋白质类(Hedgehog Proteins);细胞增殖(Cell Proliferation);数据库, 事实型(Databases, Factual);小脑肿瘤(Cerebellar Neoplasms);辅阻遏蛋白质类(Co-Repressor Proteins)

DOI 10.1016/j.neo.2023.100926

PMID 37597490

发布时间 2023-10-02

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