Abnormal myosin post-translational modifications and ATP turnover time associated with human congenital myopathy-related RYR1 mutations.

导出 OA

翻译打印收藏纠错

作者： Alexander,Sonne ^[1] ; Anna Katarina,Antonovic ^[2] ; Elise,Melhedegaard ^[1] ; Fariha,Akter ^[2] ; Jesper L,Andersen ^[3] ; Heinz,Jungbluth ^[4] ; Nanna,Witting ^[5] ; John,Vissing ^[6] ; Edmar,Zanoteli ^[7] ; Arianna,Fornili ^[7] ; Julien,Ochala ^[8]

作者单位： Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. ^[1] Department of Chemistry, School of Physical and Chemical Sciences, Queen Mary University of London, London, UK. ^[2] Department of Orthopaedic Surgery, Institute of Sports Medicine Copenhagen, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark. ^[3] Center for Healthy Aging, Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark. ^[4] Department of Paediatric Neurology, Evelina London Children's Hospital, London, UK. ^[5] Randall Centre for Cell and Molecular Biophysics, Muscle Signalling Section, Faculty of Life Sciences and Medicine, King's College London, London, UK. ^[6] Copenhagen Neuromuscular Center, Department of Neurology, University of Copenhagen, Copenhagen, Denmark. ^[7] Departamento de Neurologia, Faculdade de Medicina, Hospital das Clínicas, Universidade de São Paulo, São Paulo, Brazil. ^[8]

关键词 ATP acetylation congenital myopathy myosin heavy chain phosphorylation relaxed state skeletal muscle