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Amphiregulin couples IL1RL1<sup>+</sup> regulatory T cells and cancer-associated fibroblasts to impede antitumor immunity.

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第一作者： Runzi,Sun

第一单位： Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

作者： Runzi,Sun ^[1] ; Hongyu,Zhao ^[2] ; David Shihong,Gao ^[1] ; Andrew,Ni ^[1] ; Haochen,Li ^[3] ; Lujia,Chen ^[3] ; Xinghua,Lu ^[3] ; Kong,Chen ^[4] ; Binfeng,Lu ^[5]

作者单位： Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. ^[1] Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA. ^[2] Department of Biomedical informatics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. ^[3] Department of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. ^[4] Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.;Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA. ^[5]

医学主题词人类(Humans);T淋巴细胞, 调节性(T-Lymphocytes, Regulatory);细胞转化, 肿瘤(Cell Transformation, Neoplastic);肿瘤微环境(Tumor Microenvironment)

DOI 10.1126/sciadv.add7399

PMID 37611111

发布时间 2024-10-18

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Amphiregulin couples IL1RL1<sup>+</sup> regulatory T cells and cancer-associated fibroblasts to impede antitumor immunity.

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Amphiregulin couples IL1RL1<sup>+</sup> regulatory T cells and cancer-associated fibroblasts to impede antitumor immunity.

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