What is a minimal clinically important difference for clinical trials in patients with disorders of consciousness? a novel probabilistic approach.

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第一作者： Martin M,Monti

第一单位： Department of Psychology, University of California Los Angeles, Los Angeles, California, United States of America.;Department of Neurosurgery, Brain Injury Research Center, University of California Los Angeles, Los Angeles, California, United States of America.

作者： Martin M,Monti ^[1] ; Norman M,Spivak ^[2] ; Brian L,Edlow ^[3] ; Yelena G,Bodien ^[4]

作者单位： Department of Psychology, University of California Los Angeles, Los Angeles, California, United States of America.;Department of Neurosurgery, Brain Injury Research Center, University of California Los Angeles, Los Angeles, California, United States of America. ^[1] Department of Neurosurgery, Brain Injury Research Center, University of California Los Angeles, Los Angeles, California, United States of America.;UCLA-Caltech Medical Scientist Training Program, David Geffen School of Medicine, UCLA, Los Angeles, California, United States of America. ^[2] Department of Neurology, Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.;Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America. ^[3] Department of Neurology, Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.;Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital and Harvard Medical School Charlestown, Massachusetts, United States of America. ^[4]

主题词人类(Humans);意识障碍(Consciousness Disorders);规范(Benchmarking);昏迷(Coma);意识(Consciousness);持续植物人状态(Persistent Vegetative State)

DOI 10.1371/journal.pone.0290290

PMID 37616196

发布时间 2023-09-17

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