Chromosomal instability and a deregulated cell cycle are intrinsic features of high-risk gastrointestinal stromal tumours with a metastatic potential.

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第一作者： Heidi Maria,Namløs

第一单位： Department of Tumor Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.

作者： Heidi Maria,Namløs ^[1] ; Ksenia,Khelik ^[1] ; Sigve,Nakken ^[1] ; Daniel,Vodák ^[2] ; Eivind,Hovig ^[3] ; Ola,Myklebost ^[4] ; Kjetil,Boye ^[1] ; Leonardo A,Meza-Zepeda ^[3]

作者单位： Department of Tumor Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway. ^[1] Centre for Cancer Cell Reprogramming, Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway. ^[2] Department of Informatics, University of Oslo, Oslo, Norway. ^[3] Bioinformatics Core Facility, Department of Core Facilities, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway. ^[4] Department for Clinical Science, University of Bergen, Bergen, Norway. ^[5] Department of Oncology, Oslo University Hospital, Oslo, Norway. ^[6] Genomics Core Facility, Department of Core Facilities, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway. ^[7]

关键词 CIN GIST LOH chromothripsis miR-34a risk classification

主题词人类(Humans);胃肠道间质肿瘤(Gastrointestinal Stromal Tumors);肿瘤复发, 局部(Neoplasm Recurrence, Local);细胞周期(Cell Cycle);复发(Recurrence);抗肿瘤药(Antineoplastic Agents)

DOI 10.1002/1878-0261.13514

PMID 37622176

发布时间 2023-11-04

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准确一般字义偏差语意偏离译文作用小提交