Therapeutic targeting of nuclear export and import receptors in cancer and their potential in combination chemotherapy.

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作者： Stella,Newell ^[1] ; Pauline J,van der Watt ^[1] ; Virna D,Leaner ^[2]

作者单位： Division of Medical Biochemistry and Structural Biology, Department of Integrative Biomedical Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa. ^[1] Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa. ^[2] UCT/SAMRC Gynaecological Cancer Research Centre, University of Cape Town, Cape Town, South Africa. ^[3]

关键词 KPNB1 XPO1 cancer combination therapy nuclear transport proteins targeted therapy

主题词人类(Humans);主动转运, 细胞核(Active Transport, Cell Nucleus);肿瘤(Neoplasms);核胞浆转运蛋白类(Karyopherins);受体, 胞质和核(Receptors, Cytoplasmic and Nuclear);抗肿瘤药(Antineoplastic Agents);药物疗法, 联合(Drug Therapy, Combination)

DOI 10.1002/iub.2773

PMID 37623925

发布时间 2024-03-22

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