Phylogenetic modeling of enhancer shifts in African mole-rats reveals regulatory changes associated with tissue-specific traits.

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作者： Elise,Parey ^[1] ; Diego,Fernandez-Aroca ^[2] ; Stephanie,Frost ^[2] ; Ainhoa,Uribarren ^[3] ; Thomas J,Park ^[4] ; Markus,Zöttl ^[5] ; Ewan,St John Smith ^[6] ; Camille,Berthelot ^[7] ; Diego,Villar ^[8]

作者单位： Institut de Biologie de l'Ecole Normale Supérieure (IBENS), Ecole Normale Supérieure, CNRS, INSERM, Université PSL, 75005 Paris, France. ^[1] Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, United Kingdom. ^[2] Cambridge Institute, Cancer Research UK and University of Cambridge, Cambridge CB2 0RE, United Kingdom. ^[3] Department of Biological Sciences and Laboratory of Integrative Neuroscience, University of Illinois at Chicago, Chicago, Illinois 60607, USA. ^[4] Department of Biology and Environmental Science, Linnaeus University, 44054 Kalmar, Sweden. ^[5] Department of Pharmacology, University of Cambridge, Cambridge CB2 1PD, United Kingdom. ^[6] Institut de Biologie de l'Ecole Normale Supérieure (IBENS), Ecole Normale Supérieure, CNRS, INSERM, Université PSL, 75005 Paris, France; d.villarlozano@qmul.ac.uk camille.berthelot@pasteur.fr. ^[7] Institut Pasteur, Université Paris Cité, CNRS UMR 3525, INSERM UA12, Comparative Functional Genomics Group, F-75015 Paris, France. ^[8] Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, United Kingdom; d.villarlozano@qmul.ac.uk camille.berthelot@pasteur.fr. ^[9]

主题词动物(Animals);种系发生(Phylogeny);基因组学(Genomics);调控序列, 核酸(Regulatory Sequences, Nucleic Acid);鼹鼠属(Mole Rats)

DOI 10.1101/gr.277715.123

PMID 37625847

发布时间 2023-11-14

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