Patient-Derived Ex Vivo Cultures and Endpoint Assays with Surrogate Biomarkers in Functional Testing for Prediction of Therapeutic Response.

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作者： Yoshiyuki,Tsukamoto ^[1] ; Yuka,Hirashita ^[1] ; Tomotaka,Shibata ^[2] ; Shoichi,Fumoto ^[3] ; Shusaku,Kurogi ^[4] ; Chisato,Nakada ^[1] ; Keisuke,Kinoshita ^[5] ; Takafumi,Fuchino ^[1] ; Kazunari,Murakami ^[2] ; Masafumi,Inomata ^[1] ; Masatsugu,Moriyama ^[2] ; Naoki,Hijiya ^[2]

作者单位： Department of Molecular Pathology, Faculty of Medicine, Oita University, 1-1 Hasama-machi, Oita 879-5593, Japan. ^[1] Department of Gastroenterology, Faculty of Medicine, Oita University, Oita 879-5593, Japan. ^[2] Department of Gastroenterological and Pediatric Surgery, Faculty of Medicine, Oita University, Oita 879-5593, Japan. ^[3] Department of Surgery, Oita Nakamura Hospital, Oita 879-5593, Japan. ^[4] Department of Urology, Faculty of Medicine, Oita University, Oita 879-5593, Japan. ^[5]

关键词 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT)collagen droplet-embedded culture drug sensitivity test (CD-DST)extracellular matrix (ECM)functional testing lactate dehydrogenase (LDH)micro-organospheres (MOSs)organs on chips patient derived cancer organoids (PDCOs)patient derived explants (PDEs)spheroid

DOI 10.3390/cancers15164104

PMID 37627132

发布时间 2023-08-28

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准确一般字义偏差语意偏离译文作用小提交