Enhancement of Bottle Gourd Oil Activity via Optimized Self-Dispersing Lipid Formulations (SDLFs) to Mitigate Isoproterenol-Evoked Cardiac Toxicity in Rats via Modulating BMP, MMP2, and miRNA-21 and miRNA-23a Genes' Expression.

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作者： Shereen S,El-Mancy ^[1] ; Sylvia A,Boshra ^[2] ; Osama S,Elnahas ^[1] ; Sahar M,Fayez ^[1] ; Nermin M,Sheta ^[1]

作者单位： Department of Pharmaceutics, Faculty of Pharmacy, October 6 University, Giza 12585, Egypt. ^[1] Department of Biochemistry, Faculty of Pharmacy, October 6 University, Giza 12585, Egypt. ^[2]

关键词 BNP MMP2 bottle gourd oil miRNAs self-dispersing lipid formulations

主题词动物(Animals);大鼠(Rats);异丙肾上腺素(Isoproterenol);基质金属蛋白酶2(Matrix Metalloproteinase 2);辅药(Excipients);南瓜属(Cucurbita);内肽酶类(Endopeptidases);脂类(Lipids);微RNAs(MicroRNAs)

DOI 10.3390/molecules28166168

PMID 37630419

发布时间 2023-08-29

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Molecules (Basel, Switzerland)

2023年28卷16期

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Enhancement of Bottle Gourd Oil Activity via Optimized Self-Dispersing Lipid Formulations (SDLFs) to Mitigate Isoproterenol-Evoked Cardiac Toxicity in Rats via Modulating BMP, MMP2, and miRNA-21 and miRNA-23a Genes' Expression.

Molecules (Basel, Switzerland)

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Enhancement of Bottle Gourd Oil Activity via Optimized Self-Dispersing Lipid Formulations (SDLFs) to Mitigate Isoproterenol-Evoked Cardiac Toxicity in Rats via Modulating BMP, MMP2, and miRNA-21 and miRNA-23a Genes' Expression.

Molecules (Basel, Switzerland)

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Molecules (Basel, Switzerland)

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