Activation of thousands of genes in the lungs and kidneys by sepsis is countered by the selective nuclear blockade.

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作者： Huan,Qiao ^[1] ; Jozef,Zienkiewicz ^[2] ; Yan,Liu ^[2] ; Jacek,Hawiger ^[3]

作者单位： Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, TN, United States. ^[1] Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, TN, United States.;Department of Veterans Affairs, Tennessee Valley Health Care System, Nashville, Tennessee, TN, United States. ^[2] Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, TN, United States.;Department of Veterans Affairs, Tennessee Valley Health Care System, Nashville, Tennessee, TN, United States.;Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, TN, United States. ^[3]

关键词 acute kidney injury (AKI)acute respiratory distress syndrome (ARDS)cecal microbiome cell-penetrating peptides (CPP)inflammation next generation sequence (NGS)nuclear transport checkpoint inhibitor (NTCI)polymicrobial sepsis

主题词人类(Humans);脓毒症(Sepsis);肾(Kidney);基因组学(Genomics);肺(Lung)

DOI 10.3389/fimmu.2023.1221102

PMID 37638006

发布时间 2024-07-24

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准确一般字义偏差语意偏离译文作用小提交