首页> Proceedings of the National Academy of Sciences of the United States of America> Myo-differentiation reporter screen reveals NF-Y as an activator of PAX3-FOXO1 in rhabdomyosarcoma.

Myo-differentiation reporter screen reveals NF-Y as an activator of PAX3-FOXO1 in rhabdomyosarcoma.

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第一作者： Martyna W,Sroka

第一单位： Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724.

作者： Martyna W,Sroka ^[1] ; Damianos,Skopelitis ^[1] ; Marit W,Vermunt ^[2] ; Jonathan B,Preall ^[1] ; Osama,El Demerdash ^[1] ; Larissa M N,de Almeida ^[1] ; Kenneth,Chang ^[1] ; Raditya,Utama ^[1] ; Berkley,Gryder ^[3] ; Giuseppina,Caligiuri ^[1] ; Diqiu,Ren ^[4] ; Benan,Nalbant ^[1] ; Joseph P,Milazzo ^[1] ; David A,Tuveson ^[1] ; Alexander,Dobin ^[1] ; Scott W,Hiebert ^[5] ; Kristy R,Stengel ^[6] ; Roberto,Mantovani ^[7] ; Javed,Khan ^[8] ; Rahul M,Kohli ^[9] ; Junwei,Shi ^[4] ; Gerd A,Blobel ^[2] ; Christopher R,Vakoc ^[1]

作者单位： Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724. ^[1] Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104. ^[2] Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH 44106. ^[3] Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104. ^[4] Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232. ^[5] Department of Cell Biology, Albert Einstein College of Medicine, New York, NY 10461. ^[6] Dipartimento di Bioscienze, Università degli Studi di Milano, 20133 Milano, Italy. ^[7] Genetics Branch, National Cancer Institute, NIH, Bethesda, MD 20892. ^[8] Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104. ^[9]

关键词 NF-Y PAX3–FOXO1 muscle myo-differentiation rhabdomyosarcoma

医学主题词 CCAAT结合因子(CCAAT-Binding Factor);细胞分化(Cell Differentiation);染色体畸变(Chromosome Aberrations);横纹肌肉瘤(Rhabdomyosarcoma);转录因子(Transcription Factors)

DOI 10.1073/pnas.2303859120

PMID 37639593

发布时间 2024-02-29

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