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HDAC6 deacetylates IDH1 to promote the homeostasis of hematopoietic stem and progenitor cells.

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第一作者: Jia,Yang
第一单位: State Key Laboratory of Medicinal Chemical Biology, Haihe Laboratory of Cell Ecosystem, Tianjin Key Laboratory of Protein Science, College of Life Sciences, Nankai University, Tianjin, China.
作者: Jia,Yang [1] ; Yang,Liu [1] ; Hanxiao,Yin [1] ; Songbo,Xie [2] ; Linlin,Zhang [1] ; Xifeng,Dong [3] ; Hua,Ni [1] ; Weiwen,Bu [1] ; Hongbo,Ma [1] ; Peng,Liu [4] ; Haiyan,Zhu [4] ; Rongxia,Guo [4] ; Lei,Sun [2] ; Yue,Wu [2] ; Juan,Qin [1] ; Baofa,Sun [1] ; Dengwen,Li [1] ; Hongbo R,Luo [5] ; Min,Liu [6] ; Chenghao,Xuan [7] ; Jun,Zhou [8]
作者单位: State Key Laboratory of Medicinal Chemical Biology, Haihe Laboratory of Cell Ecosystem, Tianjin Key Laboratory of Protein Science, College of Life Sciences, Nankai University, Tianjin, China. [1] Center for Cell Structure and Function, College of Life Sciences, Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Shandong Normal University, Jinan, China. [2] Department of Hematology, Tianjin Medical University General Hospital, Tianjin, China. [3] State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China. [4] Department of Pathology, Department of Laboratory Medicine, Harvard Medical School, Children's Hospital Boston, Dana-Farber/Harvard Cancer Center, Boston, MA, USA. [5] Laboratory of Tissue Homeostasis, Haihe Laboratory of Cell Ecosystem, Tianjin, China. [6] The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Key Laboratory of Immune Microenvironment and Disease of the Ministry of Education, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China. [7] State Key Laboratory of Medicinal Chemical Biology, Haihe Laboratory of Cell Ecosystem, Tianjin Key Laboratory of Protein Science, College of Life Sciences, Nankai University, Tianjin, China.;Center for Cell Structure and Function, College of Life Sciences, Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Shandong Normal University, Jinan, China. [8]
DOI 10.15252/embr.202256009
PMID 37642636
发布时间 2024-08-30
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