Single-cell sequencing of a novel model of neonatal bile duct ligation in mice identifies macrophage heterogeneity in obstructive cholestasis.

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作者： Swati,Antala ^[1] ; Kyle D,Gromer ^[2] ; Gaurav,Gadhvi ^[1] ; Alyssa,Kriegermeier ^[3] ; Jiao-Jing,Wang ^[1] ; Hiam,Abdala-Valencia ^[4] ; Joshua B,Wechsler ^[5] ; Harris,Perlman ^[1] ; Deborah R,Winter ^[3] ; Zheng J,Zhang ^[3] ; Richard M,Green ^[4] ; Sarah A,Taylor ^[4]

作者单位： Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, IL, USA. ^[1] Division of Hepatology, Department of Pediatrics, Kravis Children's Hospital at Mount Sinai, New York, NY, USA. ^[2] Division of Rheumatology, Department of Medicine, Northwestern University, Chicago, IL, USA. ^[3] Department of Surgery, Comprehensive Transplant Center, Northwestern University, Chicago, IL, USA. ^[4] Division of Pulmonary and Critical Care Medicine, Northwestern University, Chicago, IL, USA. ^[5] Division of Gastroenterology and Hepatology, Department of Medicine, Northwestern University, Chicago, IL, USA. ^[6] Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, IL, USA. sarah.taylor2@childrenscolorado.edu. ^[7] Division of Gastroenterology and Hepatology, Department of Pediatrics, Children's Hospital Colorado, University of Colorado School of Medicine, 13123 E. 16th Ave., Box B290, Aurora, CO, 80045, USA. sarah.taylor2@childrenscolorado.edu. ^[8]