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The replication-competent HIV reservoir is a genetically restricted, younger subset of the overall pool of HIV proviruses persisting during therapy, which is highly genetically stable over time.

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第一作者: Aniqa,Shahid
第一单位: Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada.
作者单位: Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada. [1] British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada. [2] Department of Microbiology, University of Washington, School of Medicine, Seattle, WA, USA. [3] UNC HIV Cure Center, Institute of Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, NC, USA. [4] Department of Medicine, University of Miami School of Medicine, Miami, FL, USA. [5] Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA. [6] Departments of Medicine and Epidemiology, University of North Carolina School of Medicine, UNC Gillings School of Global Public Health, Chapel Hill, NC, USA. [7] Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. [8] College of Dentistry, New York University, New York, NY, USA. [9] Department of Epidemiology and Biostatistics, University at Albany, State University of New York, Rensselaer, New York, NY, USA. [10] Division of Infectious Diseases and Tropical Medicine, Georgetown University, Washington, DC, USA. [11] Departments of Microbiology and Immunology and Pediatrics, Albert Einstein College of Medicine, Bronx, New York, NY, USA. [12] Department of Medicine, Albert Einstein College of Medicine, New York, NY, USA. [13]
DOI 10.21203/rs.3.rs-3259040/v1
PMID 37645749
发布时间 2025-06-11
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