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首页> Phytomedicine : international journal of phytotherapy and phytopharmacology> Mechanisms underlying large-leaf yellow tea mediated inhibition of cognitive impairment in the 5xFAD model of Alzheimer's disease.

Mechanisms underlying large-leaf yellow tea mediated inhibition of cognitive impairment in the 5xFAD model of Alzheimer's disease.

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作者： Xiaoyu,Tang ^[1] ; Zhipeng,Kan ^[2] ; Na,Li ^[1] ; Jinbao,Huang ^[1] ; Jinsong,Zhang ^[1] ; Henry J,Thompson ^[3] ; Feng,Gao ^[2] ; Yong,Shen ^[2] ; Liang,Zhang ^[1] ; Zhongwen,Xie ^[1] ; Xiaochun,Wan ^[4] ; Yijun,Wang ^[5]

作者单位： The State Key Laboratory of Tea Plant Biology and Utilization, School of Tea & Food Science, Anhui Agricultural University, Hefei, China. ^[1] Neurodegenerative Disease Research Center, University of Science and Technology of China, Hefei, China. ^[2] Cancer Prevention Laboratory, Colorado State University, Fort Collins, CO 80523, United States. ^[3] The State Key Laboratory of Tea Plant Biology and Utilization, School of Tea & Food Science, Anhui Agricultural University, Hefei, China. Electronic address: xcwan@ahau.edu.cn. ^[4] The State Key Laboratory of Tea Plant Biology and Utilization, School of Tea & Food Science, Anhui Agricultural University, Hefei, China. Electronic address: yijun@ahau.edu.cn. ^[5]

关键词 Alzheimer's disease Amyloid-β Cognitive impairment Large-leaf yellow tea Tau hyperphosphorylation

主题词动物(Animals);小鼠(Mice);阿尔茨海默病(Alzheimer Disease);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);淀粉样前体蛋白分泌酶类(Amyloid Precursor Protein Secretases);糖尿病, 2型(Diabetes Mellitus, Type 2);天冬氨酸内肽酶类(Aspartic Acid Endopeptidases);淀粉样β肽类(Amyloid beta-Peptides);茶(Tea)

DOI 10.1016/j.phymed.2023.155030

PMID 37651754

发布时间 2023-09-25

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