Extending the vision of adaptive point-of-care platform trials to improve targeted use of drug therapy regimens: An agile approach in the learning healthcare system toolkit.

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第一作者： Gigi,Hirsch

第一单位： Center for Biomedical System Design & NEWDIGS, Tufts Medical Center, Boston, MA, USA. Electronic address: Gigi.Hirsch@tuftsmedicine.org.

作者： Gigi,Hirsch ^[1] ; Priscilla,Velentgas ^[2] ; Jeffrey R,Curtis ^[3] ; Kay,Larholt ^[4] ; Jay J H,Park ^[5] ; Chris L,Pashos ^[6] ; Ludovic,Trinquart ^[7]

作者单位： Center for Biomedical System Design & NEWDIGS, Tufts Medical Center, Boston, MA, USA. Electronic address: Gigi.Hirsch@tuftsmedicine.org. ^[1] Merck Epidemiology, Inc., Boston, MA, USA. ^[2] Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA; Illumination Health, Hoover, AL, USA. ^[3] Center for Biomedical System Design & NEWDIGS, Tufts Medical Center, Boston, MA, USA. ^[4] Core Clinical Sciences Inc, Vancouver, BC, Canada; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada. ^[5] Genesis Research, Hoboken, NJ, USA. ^[6] Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, USA; Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA, USA. ^[7]

关键词 Adaptive point-of-care platform trials Learning healthcare system Multi-stakeholder system design Sequential multiple assignment randomized trial (SMART) design

DOI 10.1016/j.cct.2023.107327

PMID 37652359

发布时间 2023-10-20

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Contemporary clinical trials

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Extending the vision of adaptive point-of-care platform trials to improve targeted use of drug therapy regimens: An agile approach in the learning healthcare system toolkit.

Contemporary clinical trials

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Extending the vision of adaptive point-of-care platform trials to improve targeted use of drug therapy regimens: An agile approach in the learning healthcare system toolkit.

Contemporary clinical trials

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Contemporary clinical trials

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