首页> In vivo (Athens, Greece)> Rapid Reduction of CEA and Stable Metastasis in an <i>NRAS</i>-mutant Rectal-Cancer Patient Treated With FOLFIRI and Bevacizumab Combined With Oral Recombinant Methioninase and a Low-Methionine Diet Upon Metastatic Recurrence After FOLFIRI and Bevacizumab Treatment Alone.

Rapid Reduction of CEA and Stable Metastasis in an <i>NRAS</i>-mutant Rectal-Cancer Patient Treated With FOLFIRI and Bevacizumab Combined With Oral Recombinant Methioninase and a Low-Methionine Diet Upon Metastatic Recurrence After FOLFIRI and Bevacizumab Treatment Alone.

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第一作者： Yutaro,Kubota

第一单位： AntiCancer Inc., San Diego, CA, U.S.A.;Department of Surgery, University of California, San Diego, CA, U.S.A.;Division of Internal Medicine, Department of Medical Oncology, Showa University School of Medicine, Tokyo, Japan.

作者： Yutaro,Kubota ^[1] ; Qinghong,Han ^[2] ; Sei,Morinaga ^[3] ; Takuya,Tsunoda ^[4] ; Robert M,Hoffman ^[5]

作者单位： AntiCancer Inc., San Diego, CA, U.S.A.;Department of Surgery, University of California, San Diego, CA, U.S.A.;Division of Internal Medicine, Department of Medical Oncology, Showa University School of Medicine, Tokyo, Japan. ^[1] AntiCancer Inc., San Diego, CA, U.S.A. ^[2] AntiCancer Inc., San Diego, CA, U.S.A.;Department of Surgery, University of California, San Diego, CA, U.S.A. ^[3] Division of Internal Medicine, Department of Medical Oncology, Showa University School of Medicine, Tokyo, Japan. ^[4] AntiCancer Inc., San Diego, CA, U.S.A.; all@anticancer.com.;Department of Surgery, University of California, San Diego, CA, U.S.A. ^[5]

关键词 CEA FOLFIRI Hoffman effect Hoffman protocol Rectal cancer bevacizumab combination therapy efficacy low-methionine diet metastasis methionine addiction methionine restriction oral recombinant methioninase