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Autocrine IL-6 drives cell and extracellular matrix anisotropy in scar fibroblasts.

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第一作者： Fiona N,Kenny

第一单位： Randall Centre for Cell and Molecular Biophysics, King's College London, London, UK.

作者： Fiona N,Kenny ^[1] ; Stefania,Marcotti ^[1] ; Deandra Belo,De Freitas ^[1] ; Elena M,Drudi ^[2] ; Vivienne,Leech ^[3] ; Rachel E,Bell ^[2] ; Jennifer,Easton ^[2] ; María-Del-Carmen,Díaz-de-la-Loza ^[1] ; Roland,Fleck ^[4] ; Leanne,Allison ^[4] ; Christina,Philippeos ^[5] ; Angelika,Manhart ^[6] ; Tanya J,Shaw ^[7] ; Brian M,Stramer ^[8]

作者单位： Randall Centre for Cell and Molecular Biophysics, King's College London, London, UK. ^[1] Centre for Inflammation Biology & Cancer Immunology, Department of Inflammation Biology, School of Immunology & Microbial Sciences, King's College London, London, UK. ^[2] Department of Mathematics, University College London, UK. ^[3] Centre for Ultrastructure Imaging, King's College London, UK. ^[4] Centre for Stem Cells and Regenerative Medicine, King's College London, London, UK. ^[5] Department of Mathematics, University College London, UK; Faculty of Mathematics, University of Vienna, Vienna, Austria. ^[6] Centre for Inflammation Biology & Cancer Immunology, Department of Inflammation Biology, School of Immunology & Microbial Sciences, King's College London, London, UK. Electronic address: tanya.shaw@kcl.ac.uk. ^[7] Randall Centre for Cell and Molecular Biophysics, King's College London, London, UK. Electronic address: brian.m.stramer@kcl.ac.uk. ^[8]

关键词 Extracellular matrix Fibroblast Fibrosis IL-6 Keloid Scar

医学主题词人类(Humans);瘢痕疙瘩(Keloid);白细胞介素6(Interleukin-6);各向异性(Anisotropy);细胞, 培养的(Cells, Cultured);细胞外基质(Extracellular Matrix);成纤维细胞(Fibroblasts)

DOI 10.1016/j.matbio.2023.08.004

PMID 37660739

发布时间 2025-09-24

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