Systemic virus infection results in CD8 T cell recruitment to the retina in the absence of local virus infection.

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作者： Egle,Paskeviciute ^[1] ; Mei,Chen ^[2] ; Heping,Xu ^[2] ; Bent,Honoré ^[3] ; Henrik,Vorum ^[4] ; Torben Lykke,Sørensen ^[4] ; Jan Pravsgaard,Christensen ^[5] ; Allan Randrup,Thomsen ^[6] ; Mogens Holst,Nissen ^[7] ; Maria Abildgaard,Steffensen ^[1]

作者单位： Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark. ^[1] Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queens University of Belfast, Belfast, Ireland. ^[2] Department of Biomedicine, Aarhus University, Aarhus, Denmark. ^[3] Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. ^[4] Department of Ophthalmology, Aalborg University Hospital, Aalborg, Denmark. ^[5] Department of Ophthalmology, Zealand University Hospital, Roskilde, Denmark. ^[6] Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark. ^[7]

关键词 CD8 T cell CXCL16 CXCR6 immune surveillance lymphocytic choriomeningitis virus (LCMV)retina retinal pigment epithelial cell

主题词动物(Animals);小鼠(Mice);病毒性疾病(Virus Diseases);脑(Brain);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);视网膜(Retina);脓毒症(Sepsis)

DOI 10.3389/fimmu.2023.1221511

PMID 37662932

发布时间 2023-09-15

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