Electrically stimulated in vitro heart cell mimic of acute exercise reveals novel immediate cellular responses to exercise: Reduced contractility and metabolism, but maintained calcium cycling and increased myofilament calcium sensitivity.

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第一作者： Ana Da Silva,Costa

第一单位： School of Cardiovascular and Metabolic Health, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.

作者： Ana Da Silva,Costa ^[1] ; Iffath,Ghouri ^[2] ; Alexander,Johnston ^[1] ; Karen,McGlynn ^[3] ; Andrew,McNair ^[1] ; Peter,Bowman ^[1] ; Natasha,Malik ^[1] ; Johanne,Hurren ^[1] ; Tomas,Bingelis ^[1] ; Michael,Dunne ^[1] ; Godfrey L,Smith ^[1] ; Ole J,Kemi ^[1]

作者单位： School of Cardiovascular and Metabolic Health, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK. ^[1] Graduate School, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK. ^[2] Wellcome Centre for Mitochondrial Research, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK. ^[3]

关键词 autofluorescence calcium cardiomyocyte cells-in-a-dish contractility exercise

主题词大鼠(Rats);动物(Animals);肌原纤维(Myofibrils);钙(Calcium);心肌收缩(Myocardial Contraction);肌细胞, 心脏(Myocytes, Cardiac);运动(Exercise)(Exercise)

DOI 10.1002/cbf.3847

PMID 37665041

发布时间 2024-03-20

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