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Inhibition of Wnt/β-catenin signaling reduces renal fibrosis in murine glycogen storage disease type Ia.

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第一作者： Cheol,Lee

第一单位： Section on Cellular Differentiation, Division of Translational Medicine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20802, USA.

作者： Cheol,Lee ^[1] ; Kunal,Pratap ^[1] ; Lisa,Zhang ^[1] ; Hung Dar,Chen ^[1] ; Sudeep,Gautam ^[1] ; Irina,Arnaoutova ^[1] ; Mahadevan,Raghavankutty ^[2] ; Matthew F,Starost ^[3] ; Michael,Kahn ^[4] ; Brian C,Mansfield ^[1] ; Janice Y,Chou ^[5]

作者单位： Section on Cellular Differentiation, Division of Translational Medicine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20802, USA. ^[1] Section on Developmental Genetics, Division of Translational Medicine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20802, USA. ^[2] Division of Veterinary Resources, National Institutes of Health, Bethesda, MD 20802, USA. ^[3] Department of Cancer Biology and Molecular Medicine, Beckmann Research Institute, City of Hope, Duarte, CA 91010, USA. ^[4] Section on Cellular Differentiation, Division of Translational Medicine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20802, USA. Electronic address: chouja@mail.nih.gov. ^[5]

关键词 Acute kidney injury Glucose reabsorption Glucose-6-phosphatase-α Nephromegaly, ICG-001 von Gierke Disease

医学主题词 β连环素(beta Catenin);糖原贮积病Ⅰ型(Glycogen Storage Disease Type I);小鼠(Mice);胶原(Collagen);急性肾损伤(Acute Kidney Injury);动物(Animals);纤维化(Fibrosis)

DOI 10.1016/j.bbadis.2023.166874

PMID 37666439

发布时间 2025-05-30

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准确一般字义偏差语意偏离译文作用小提交