CCDC50 promotes tumor growth through regulation of lysosome homeostasis.

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作者： Penghui,Jia ^[1] ; Tian,Tian ^[2] ; Zibo,Li ^[1] ; Yicheng,Wang ^[1] ; Yuxin,Lin ^[1] ; Weijie,Zeng ^[1] ; Yu,Ye ^[1] ; Miao,He ^[1] ; Xiangrong,Ni ^[3] ; Ji'an,Pan ^[1] ; Xiaonan,Dong ^[4] ; Jian,Huang ^[5] ; Chun-Mei,Li ^[1] ; Deyin,Guo ^[4] ; Panpan,Hou ^[6]

作者单位： MOE Key Laboratory of Tropical Disease Control, Centre for Infection and Immunity Study (CIIS), School of Medicine, Sun Yat-sen University, Shenzhen, China. ^[1] The Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. ^[2] Department of Neurosurgery/Neuro-oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangzhou, China. ^[3] Guangzhou Laboratory, Guangzhou International Bio-Island, Guangzhou, China. ^[4] Coriell Institute for Medical Research, Camden, NJ, USA. ^[5] MOE Key Laboratory of Tropical Disease Control, Centre for Infection and Immunity Study (CIIS), School of Medicine, Sun Yat-sen University, Shenzhen, China.;State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. ^[6]

关键词 CCDC50 cell death lysophagy lysosome damage melanoma