换一批NHWD-870 protects the kidney from ischemia/reperfusion injury by upregulating the PI3K/AKT signaling pathway (experimental study).
第一作者：
Saba Sahib,Younis
第一单位：
Al-Sadr Medical City, Al-Najaf Health Directorate, Al Najaf Al-Ashraf, Iraq.
作者：
关键词
AKI: Acute Kidney InjuryBCL-2BCL-2: B-cell lymphoma-2BUN: Blood Urea NitrogenDMSO: Dimethyl SulfoxideELISA: Enzyme-Linked Immunosorbent AssayI/R: Ischemia ReperfusionIL-1BIL-1B: Interleukin-1 BetaNHWD-870P-Akt: Phosphorylated-Protein Kinase BPGF-2PI3K/AKTPI3K: Phosphatidylinositide 3-KinasesRIRI: Renal Ischemia-Reperfusion InjuryROS: Reactive Oxygen SpeciesSCr: Serum Creatinineischemia reperfusion injury
主题词
男(雄)性(Male);动物(Animals);大鼠(Rats);大鼠, Wistar(Rats, Wistar);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);抗氧化剂(Antioxidants);核蛋白质类(Nuclear Proteins);转录因子(Transcription Factors);再灌注损伤(Reperfusion Injury);肾(Kidney);信号传导(Signal Transduction)
DOI
10.25122/jml-2022-0309
PMID
37675155
发布时间
2023-11-06
- 浏览2
Journal of medicine and life
925-931页
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